Publications by authors named "N P Barnett"
Background: Central nervous system (CNS)-active polypharmacy (defined as concurrent exposure to three or more antidepressant, antipsychotic, antiseizure, benzodiazepine, opioid, or nonbenzodiazepine benzodiazepine receptor agonists) is associated with significant potential harms in persons living with dementia (PLWD).We conducted a pilot trial to assess a patient nudge intervention's implementation feasibility and preliminary effectiveness to prompt deprescribing conversations between PLWD experiencing CNS-active polypharmacy and their primary care clinicians ("clinicians").
Methods: We used the electronic health record to identify PLWD prescribed CNS-active polypharmacy in primary care clinics from two health systems.
Interhospital Variability in 180-day Infections Following Cardiac Surgery.
J Thorac Cardiovasc Surg
January 2025
Objective: This study sought to: (1) evaluate hospital-level variation in infections following cardiac surgery and (2) develop and evaluate a 180-day infection quality metric.
Methods: This study evaluated Medicare claims that were merged with institutional Society of Thoracic Surgeons Adult Cardiac Surgery Database files among patients undergoing cardiac surgery across 33 Michigan centers. The primary outcome was an infection within 180 days of surgery.
Objective: To examine prospectively the relationship between teething and infant sleep using objective sleep measurements.
Study Design: Over a 4-week period, 849 infants aged 3-18 months (mean = 8.4 ± 1.
Article Synopsis
- Caudal blocks are a pediatric anesthesia technique used to manage pain after circumcision; this study aimed to compare the duration of the block when using a high-volume, low-concentration (HVLC) local anesthetic with and without the addition of clonidine.
- The study included 129 children aged 0-3 years and measured the effectiveness of pain relief based on how long patients waited before needing additional acetaminophen; no significant differences were found between the clonidine and no-clonidine groups regarding pain management or emergence agitation.
- Overall, the addition of clonidine did not significantly improve the outcomes of HVLC caudal blocks for children undergoing circumcision.