Publications by authors named "N P Baranov"

Article Synopsis
  • This study explored how gynaecologists and trainees perceive shared decision-making (SDM) in comparison to other medical cases, using 'job satisfaction' and 'complexity' as key criteria for ranking.
  • Results showed that participants felt more satisfaction from technical cases than from emotional or SDM cases, with technical tasks considered less complex than emotional ones.
  • The study suggests that gynaecologists may be less satisfied with SDM due to its complexity and the discomfort it brings, highlighting the need for integrating SDM into their routine and fostering an environment that supports non-technical interactions.
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Article Synopsis
  • Interpretation of noncoding genomic variants is a major challenge in human genetics, and recent machine learning methods have shown promise in predicting their effects.
  • Current methods rely on specific experimental data for training, which limits their applicability across different cell types with unmeasured features.
  • The new DeepCT neural network architecture can learn from sparse epigenetic data, infer missing information, and provide cell type-specific predictions regarding the impact of noncoding variations in the genome.
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Background: The number of older patients undergoing curative esophagectomy for esophageal cancer is increasing, and minimally invasive techniques are being increasingly used. The aim of this study is to compare postoperative outcomes after curative esophagectomy between older and younger patients.

Methods: Data was retrieved from the Dutch Upper Gastrointestinal Cancer Audit (DUCA), a national surgical outcome registry.

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Background: Data on the age-specific incidence of esophageal cancer are lacking. Our aim was to investigate the age-stratified incidence, treatment, and survival trends of esophageal cancer in the Netherlands, with a focus on adults <50 years.

Material And Methods: Patients diagnosed with esophageal cancer were included from the nationwide Netherlands Cancer Registry (1989-2018).

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New polymer-bioactive compound systems were obtained by immobilization of triazole derivatives onto grafted copolymers and grafted copolymers carrying betaine units based on gellan and N-vinylimidazole. For preparation of bioactive compound, two new types of heterocyclic thio-derivatives with different substituents were combined in a single molecule to increase the selectivity of the biological action. The 5-aryl-amino-1,3,4 thiadiazole and 5-mercapto-1,2,4-triazole derivatives, each containing 2-mercapto-benzoxazole nucleus, were prepared by an intramolecular cyclization of thiosemicarbazides-1,4 disubstituted in acidic and basic medium.

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