Publications by authors named "N Oyen"
Background: More women with congenital heart disease (CHD) reach reproductive age, but little is known of their success in having children. We investigated time trends of CHD in women of reproductive age and maternal CHD in childbirth and compared birth rates in women with CHD to birth rates in women without heart disease.
Methods And Results: In a national cohort, we combined information from five registries in Norway 1994-2014.
Article Synopsis
- Objective
- : The study aimed to investigate the link between maternal diabetes during pregnancy and subtle changes in the heart structure and function of infants, specifically looking at the effects of both preexisting diabetes and gestational diabetes mellitus (GDM).
- Methods
- : Researchers analyzed data from 25,486 infants who underwent heart ultrasound within their first two months. They used linear regression to evaluate differences in heart measurements between infants exposed to maternal diabetes and those who were not.
- Results
- : Infants whose mothers had preexisting diabetes showed significant changes like thicker heart walls, smaller heart dimensions, lower blood flow, and faster heart rates compared to unexposed infants. Those born to mothers with GDM had similar,
Introduction: The prevalence of congenital heart disease (CHD) among women of reproductive age is rising. We aimed to investigate the risk of preeclampsia and adverse neonatal outcomes in pregnancies of mothers with CHD compared to pregnancies of mothers without heart disease.
Material And Methods: In a nationwide cohort of pregnancies in Norway 1994-2014, we retrieved information on maternal heart disease, the course of pregnancy, and neonatal outcomes from national registries.
Risk of Congenital Heart Defects in Offspring of Affected Mothers and Fathers.
Circ Genom Precis Med
August 2022
Background: Smaller studies have reported a higher offspring risk of congenital heart defects (CHDs) for mothers with CHDs than for fathers with CHDs. In a large population-based study, we investigated whether offspring risk of CHD differed for mothers and fathers with CHDs.
Methods: All people born in Denmark, 1977 to 2011, with at least 1 registered parent, were included in our cohort (n=2 341 061).
The association between folic acid supplementation and birth defects other than neural tube defects (NTD) remains unclear. We used a log-binomial regression model to investigate if periconceptional folic acid and/or multivitamin use was associated with birth defects in Norway with prospectively collected data from the Medical Birth Registry of Norway (MBRN) during 1999-2013. We used the European Surveillance of Congenital Anomalies (EUROCAT) classification system to define eleven organ-specific major birth defect groups (nervous system, eye, ear-face-neck, cardiovascular system, respiratory system, oral clefts, digestive system, abdominal wall, urinary system, genital organs and limb), with additional subgroups.
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