Publications by authors named "N Omori"

Background: Despite being the most prevalent neurodevelopmental disorders, there are comparatively few treatment options available to patients presenting with autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD). The ketogenic diet has historically shown therapeutic utility in treating refractory epilepsy, an adjacent neuropsychiatric condition, in children, adolescents and adults. The following review explores preclinical and clinical literature focusing on the therapeutic potential of the ketogenic diet and exogenous ketone body supplementation in treating common neurodevelopmental disorders.

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Introduction: Anemia is a risk factor for dementia development. However, few studies have examined the relationship between brain volume and anemia. This study aimed to analyze the association between anemia and brain volume using magnetic resonance imaging data from brain health checkups.

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The hollow fiber membrane bundle is the functional component of artificial lungs, transferring oxygen to and carbon dioxide from the blood. It is also the primary location of blood clot formation and propagation in these devices. The geometric design of fiber bundles is defined by a narrow set of parameters that determine gas exchange efficiency and blood flow resistance, principally: fiber packing density, path length, and frontal area.

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Article Synopsis
  • The study investigates the relationship between smoking and the severity of cerebral small-vessel disease (CSVD) in healthy individuals aged 50 and older, highlighting that smoking is a known risk factor for cognitive decline and stroke.
  • Researchers analyzed data from over 2,000 participants, examining factors like age, BMI, and smoking history in relation to CSVD lesions identified through MRI scans.
  • Findings reveal that current smokers had a higher risk of enlarged perivascular spaces in the basal ganglia based on their smoking history, while no significant associations were found for past smokers or other CSVD lesions.
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  • Atrial functional mitral regurgitation (AFMR) is under-researched, leading to a need for understanding its prevalence, characteristics, and treatment outcomes.
  • A study conducted across 26 Japanese medical centers reviewed echocardiography data from 177,235 patients, identifying 1,007 cases of AFMR, predominantly in older adults, with a significant portion also having atrial fibrillation.
  • Among AFMR patients, 113 underwent mitral valve surgery, often alongside tricuspid valve intervention, revealing that these patients had more severe mitral regurgitation and higher associated heart failure rates compared to those who did not have surgery.
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