Publications by authors named "N Okuno"

Background/aims: Biliary obstruction drainage in patients with hepatocellular carcinoma (HCC) is associated with symptom palliation, improved access to chemotherapy, and improved survival. Stent placement and exchange via endoscopic retrograde cholangiopancreatography biliary drainage risk traversing the HCC, a hypervascular tumor and causing bleeding. Endoscopic ultrasound-guided hepaticogastrostomy (EUS-HGS) potentially prevents procedure-related bleeding.

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Background/aims: Hepatobiliary scintigraphy (HBS) is used to evaluate bile excretion. This study aimed to evaluate biliary excretion during endoscopic ultrasound-guided hepaticogastrostomy (EUS-HGS) using HBS.

Methods: We retrospectively evaluated 78 consecutive patients with malignant extrahepatic biliary obstruction, who underwent HBS after EUS-HGS between April 2015 and July 2022.

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Article Synopsis
  • - Median arcuate ligament syndrome results in the celiac artery being compressed, leading to reduced blood flow and potential aneurysm formation in the pancreatic area; it was observed in six cases during the COVID-19 pandemic.
  • - Patients experienced abdominal pain 3 to 9 days after COVID-19 onset, although none required oxygen, and diagnoses were confirmed using contrast-enhanced CT scans showing hemorrhage and aneurysms.
  • - While rare, retroperitoneal hemorrhage related to this syndrome may be exacerbated by COVID-19, causing complications like duodenal stenosis and portal vein thrombosis in some patients.
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Endoscopic ultrasonography (EUS)-guided ethanol injection (EI) has recently been introduced as one of the management strategies for pancreatic neuroendocrine neoplasms (PNENs); however, its role as a surgical alternative is unclear. We evaluated the efficacy and safety of EUS-EI in treating small PNENs through a prospective multicenter study.Patients with grade 1 tumors of ≤15 mm confirmed by pathology were included.

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Alveolar rhabdomyosarcoma (ARMS) is a malignant tumor with skeletal muscle differentiation that usually occurs in soft tissues of the extremities or trunk. To date, only a few cases of primary gastric ARMS have been reported. Herein, we describe a case of ARMS in a man in his 80s and present a literature review.

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