Publications by authors named "N Okun"
Background: Rheumatic heart disease (RHD) remains as 1 of the major contributors to indirect pregnancy-related mortality and morbidity worldwide and disproportionately affects marginalized populations.
Objectives: In this scoping review, the authors sought to explore the socioeconomic, cultural, and health care access-related causes of global disparities in outcomes of pregnancy among individuals with RHD.
Methods: We performed a literature search of all studies published between January 1, 1990, and January 1, 2022, that investigated causes for disparate outcomes in pregnant individuals with RHD.
Background: Preeclampsia significantly impacts maternal and perinatal health. Early screening using advanced models and primary prevention with low-dose acetylsalicylic acid for high-risk populations is crucial to reduce the disease's incidence. This study assesses the feasibility of implementing preterm preeclampsia screening and prevention by leveraging information from our current aneuploidy screening program in a real-world setting with geographic separation clinical site and laboratory analysis site.
View Article and Find Full Text PDFObjectives: This study aimed to estimate the association between low first-trimester maternal serum PlGF (placental growth factor) and PAPP-A (pregnancy-associated plasma protein A) and the risk of placenta-mediated complications.
Methods: We performed a secondary analysis of the PREDICTION study, including nulliparous participants recruited at 11 to 14 weeks of pregnancy. First-trimester PlGF and PAPP-A levels were reported in multiples of the median (MoM) adjusted for maternal characteristics and gestational age.
Guideline No. 456: Prenatal Screening for Fetal Chromosomal Anomalies.
J Obstet Gynaecol Can
November 2024
Article Synopsis
- The document reviews available prenatal aneuploidy screening options and updates clinical guidelines to help reproductive care providers offer better counseling to pregnant individuals.
- It highlights the importance of proper guidance due to the variety of screening methods, their costs, and potential anxiety caused by decision-making processes regarding prenatal tests.
- Evidence was gathered from reputable medical sources, and the quality of the recommendations was rated using a systematic approach to ensure reliability for health care providers involved in prenatal screening.