Publications by authors named "N Okeke"

Article Synopsis
  • The study aimed to assess the exposure levels of the Lassa virus (LASV) in two urban areas of Nigeria to inform preventive measures against Lassa fever outbreaks.* -
  • Conducted from February to July 2022, the research involved collecting and analyzing serum samples from 628 participants in Abuja and Lagos for LASV antibodies while gathering sociodemographic data through questionnaires.* -
  • Results showed a 27% overall seroprevalence of LASV antibodies, with higher rates in Abuja (33%) compared to Lagos (18%), and identified factors like the dry season, inconsistent washing of produce, and positive malaria tests as linked to higher seropositivity in Abuja.*
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A subset of patients with chronic hepatitis C virus (HCV) infection demonstrate liver enzyme elevation (LEE) after achieving sustained virologic response (SVR). Risk factors for LEE are not well characterised. We conducted a single-centre retrospective cohort study of adults with HCV infection in the Duke University Health System who received direct-acting antiviral therapy and achieved SVR.

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The increased incidence of chronic diseases among people with HIV (PWH) is poised to increase the need for specialty care outside of HIV treatment settings. To reduce outcome disparities for HIV-associated comorbidities in the United States, it is critical to optimize access to and the quality of specialty care for underrepresented racial and ethnic minority (URM) individuals with HIV. We explored the experiences of URM individuals with HIV and other comorbidities in the specialty care setting during their initial and follow-up appointments.

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Climate change poses one of the most significant modern threats to overall human health,especially for vulnerable populations including persons living with HIV (PLWH). In this perspective, we specifically explore the concept of immune resilience in human health and how climate change phenomena - including extreme weather events, food insecurity, pollution, and emerging diseases - may exacerbate immune dysfunction and comorbidities faced by PLWH and hinder access to HIV treatment and prevention services. Multidisciplinary, collaborative efforts are urgently needed to quantify these impacts, develop mitigation strategies, and strengthen policies and funding to bolster immune resilience for PLWH in the face of accelerating climate change.

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