[The subcellular mechanisms of the action of disinfectants. The effect of iodine and chloramine-B on bacterial ribosomes].

The composition of ribosomal material in bacterial cells of 5 families, subjected to the minimal bactericidal action of iodine and chloramine-B, was studied with the use of electrophoresis in polyacrylamide gel. The study demonstrated that under these conditions protein-synthesizing organelles of vibrios and bifidobacteria did not undergo perceptible changes, while Escherichia, Pseudomonas and bacilli essential ribosomal degradation was found to occur, which was manifested by a decrease in the intensity of bands 23S and 16S of ribosomal RNA. The conclusion was made that the in vivo destruction of ribosomes was not the direct result of the action of disinfectants, but mediated by some cellular mechanisms.

[The use of the enteric sorbent "Silard P" in comprehensive treatment of diabetic foot syndrome].

The expediency of enterosorption application in complex treatment of the purulent-necrotic affection of foot in patients with diabetes mellitus was substantiated. The results of treatment of 36 patients, in 16 of whom enterosorpent "Silard P" was applied and in 20--the generally-accepted complex therapy, were analyzed.

[Humoral immunity in patients with diabetes mellitus and diabetic foot].

The humoral immunity peculiarities were studied in 40 patients with diabetic foot syndrome. Immunoglobulin spectrum changes were analyzed in different types of diabetes mellitus.