Publications by authors named "N Nzoyikorera"
We describe cases with monkeypox virus (MPXV) Clade Ib in Burundi from their first detection in July until 20 August 2024. Testing 442 people with vesicular lesions confirmed 170 cases (98 male; 72 female), 82 (48%) being < 15 years old. Differential diagnosis of the first 30 individuals testing MPXV negative revealed chickenpox in 20.
View Article and Find Full Text PDFDuring the 3 years following the emergence of the COVID-19 pandemic, the African continent, like other regions of the world, was substantially impacted by COVID-19. In Morocco, the COVID-19 pandemic has been marked by the emergence and spread of several SARS-CoV-2 variants, leading to a substantial increase in the incidence of infections and deaths. Nevertheless, the comprehensive understanding of the genetic diversity, evolution, and epidemiology of several viral lineages remained limited in Morocco.
View Article and Find Full Text PDFBackground: Streptococcus pneumoniae, a major contributor to global morbidity and mortality, disproportionately affects children, the elderly, and immunocompromised individuals. Despite vaccination efforts, the challenge of serotype replacement highlights the ongoing struggle against invasive pneumococcal diseases (IPD) in Morocco, emphasizing the need for updated public health strategies and vaccine efficacy assessments.
Methods: This study was conducted at the Ibn Rochd University Hospital Center and the Mohammed VI University Hospital Center from 2019 to 2022, focusing on hospitalized children.
The East African Community (EAC) is experiencing an unprecedented, emerging mpox outbreak since July 2024 in five of eight partner states. We highlight rapid regional response measures, initiated August 2024 coordinated by EAC: field deployment of six mobile laboratories in Burundi, Rwanda, Uganda, Tanzania, Kenya, South Sudan to high-risk areas, donation of one mobile laboratory to Democratic Republic of the Congo and genomic monkeypox virus (MPXV) surveillance support. These interventions aim to limit local mpox spread and support international containment.
View Article and Find Full Text PDFArticle Synopsis
- The East African Community (EAC) faces significant challenges in addressing infectious diseases and antimicrobial resistance (AMR), highlighting an urgent need for improved pathogen genomics capabilities across its member states.
- A study showed stark differences in how EAC countries utilize bacterial pathogen sequencing; nearly all quality genome data (97%) was processed by external organizations, primarily outside of Africa, with Tanzania, Kenya, and Uganda leading in local sequencing efforts.
- Key obstacles include a lack of local sequencing facilities, limited bioinformatics skills, insufficient computing resources, and weak data-sharing practices, all of which hinder the region's public health laboratories from effectively using pathogen genomics for AMR surveillance and outbreak response.