Publications by authors named "N Ntusi"
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- The study investigates how co-occurring HIV and tuberculosis (TB) affect the heart's efficiency in adolescents with HIV acquired at birth (APHIV) in Cape Town, South Africa.
- Researchers hypothesized that APHIV individuals who had previous TB would show worse cardiovascular health due to increased inflammation and disrupted metabolism.
- Results indicated that APHIV with prior TB had lower cardiac efficiency compared to those without TB, but this was not linked to traditional markers of inflammation or lipid levels, suggesting other factors may be involved.
Background: It is unclear how rising obesity among people with HIV (PWH) impacts their risk of type 2 diabetes mellitus (diabetes). We examined associations between HIV, prevalent diabetes and adiposity among South African PWH and their peers without HIV (PWOH).
Methods: HIV status was ascertained by antibody testing.
Background: Type 2 diabetes mellitus (T2DM) may be a long-term sequela of infection with () by mechanisms that remain to be fully explained. We evaluated the association between sensitization and T2DM and, via mediation analysis, the extent to which it is mediated by insulin resistance and/or β-cell failure.
Methods: Adults were assessed for T2DM by fasting plasma glucose, 2-hour oral glucose tolerance testing, and hemoglobin A; β-cell dysfunction and insulin resistance by homoeostasis model assessment 2; and sensitization by tuberculin skin testing.