Publications by authors named "N Noda"
Droplet microfluidic-based technology is a powerful tool for biotechnology, and it is also expected that it will be applied to culturing and screening methods. Using this technology, a new high-throughput screening method for lactic acid bacteria was developed. In this study, the conventional culture of lactic acid bacteria that form clear zones on an agar medium was reproduced in water-in-oil droplets, and only the droplets in which lactic acid bacteria grew were collected one by one.
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- The study investigates the role of serum and bronchoalveolar lavage fluid (BALF) markers KL-6, SP-A, and SP-D in predicting the prognosis of chronic fibrosing interstitial pneumonia (CFIP).
- By analyzing 39 patients with CFIP, researchers categorized them into rapidly progressing or slowly progressing groups based on their yearly decline in lung function.
- Results indicated that specific BALF marker levels and ratios were significantly lower in the rapidly progressing group, highlighting their potential utility in diagnosing and predicting disease progression in CFIP patients.
Article Synopsis
- * In the resection group, 76.2% achieved complete tumor removal, but 14.3% had regrowth; in contrast, 86.5% of the radiosurgery group maintained tumor control, with fewer complications related to facial nerve function.
- * Results highlighted that patients with specific tumor characteristics, like large cysts and rapid growth, may benefit more from surgical resection, while radiosurgery is preferable for preserving facial function.
Eukaryotic genomes are organized by condensin into 3D chromosomal architectures suitable for chromosomal segregation during mitosis. However, molecular mechanisms underlying the condensin-mediated chromosomal organization remain largely unclear. Here, we investigate the role of newly identified interaction between the Cnd1 condensin and Pmc4 mediator subunits in fission yeast, Schizosaccharomyces pombe.
View Article and Find Full Text PDFCongenital antithrombin (AT) or serpin C1 deficiency, caused by a SERPINC1 abnormality, is a high-risk factor for venous thrombosis. SERPINC1 is prone to genetic rearrangement, because it contains numerous Alu elements. In this study, a Japanese patient who developed deep vein thrombosis during pregnancy and exhibited low AT activity underwent SERPINC1 gene analysis using routine methods: long-range polymerase chain reaction (PCR) and real-time PCR.
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