Nanoliposomal system for augmented antibacterial and antiproliferative efficacy of L. extract.

Objective: This study focused on the nanoliposomal encapsulation of bioactive compounds extracted from L. (ME) using ethanol as a strategy to improve the antibacterial activity, anticytotoxic, and antiproliferative properties.

Methods: Nanoliposomes loaded with ME (MEL) were characterized for total phenolic content, particle size, polydispersity, and encapsulation efficiency.

A Novel Technique for Fluorescence Lifetime Tomography.

Fluorescence lifetime has emerged as a unique imaging modality for quantitatively assessing the molecular environment of diseased tissues. Although fluorescence lifetime microscopy (in 2D) is a mature field, 3D imaging in deep tissues remains elusive and challenging owing to scattering. Herein, we report on a deep neural network (coined AUTO-FLI) that performs both 3D intensity and quantitative lifetime reconstructions in deep tissues.

Mental health status among chronic disease patients in Bangladesh during the COVID-19 Pandemic: Findings from a cross-sectional study.

Context: The COVID-19 epidemic has had a substantial influence on the mental health of chronic disease patients. However, there is a scarcity of research on them in Bangladesh.

Aims: This study aims to explore the prevalence of and identify the risk factors for depression, anxiety, and stress symptoms during the COVID-19 pandemic among people with chronic diseases in Bangladesh.

Bakuchiol, a natural constituent and its pharmacological benefits.

Background And Aims: Natural compounds extracted from medicinal plants have recently gained attention in therapeutics as they are considered to have lower Toxicity and higher tolerability relative to chemically synthesized compounds. Bakuchiol from L. is one such compound; it is a type of meroterpene derived from the leaves and seeds of plants.

T helper cell responses in adult diarrheal patients following natural infection with enterotoxigenic are primarily of the Th17 type.

Background: Infection with enterotoxigenic (ETEC) gives rise to IgA antibodies against both the heat labile toxin (LT) and colonization factors (CFs), which are considered to synergistically protect against ETEC diarrhea. Since the development of ETEC-specific long lived plasma cells and memory B cells is likely to be dependent on T helper (Th) cells, we investigated if natural ETEC diarrhea elicits ETEC-specific Th cells and their relation to IgA responses.

Methods: Th cell subsets were analyzed in adult Bangladeshi patients hospitalized due to ETEC diarrhea by flow cytometric analysis of peripheral blood mononuclear cells (PBMCs) isolated from blood collected day 2, 7, 30 and 90 after hospitalization as well as in healthy controls.