Publications by authors named "N Nikas"

Introduction: Patients with chronic obstructive pulmonary disease (COPD) often report deteriorated functional status and poor health-related quality of life, both core aspects of their overall health status. The study objective was to assess tiotropium/olodaterol Respimat effects on health and functional status of COPD patients requiring long-acting dual bronchodilation treatment in the real world.

Methods: ELLACTO was an open-label, observational, prospective study conducted in Greece, measuring changes on health and functional status of COPD patients treated with a fixed dose of tiotropium/olodaterol Respimat for approximately 6 weeks.

View Article and Find Full Text PDF

Background: To estimate the incidence of hemorrhagic events in patients with atrial fibrillation (AF) treated with acenocoumarol, and the management cost of those requiring hospitalization in Greece.

Methods: A nationwide telephone survey was conducted between December 2017 and January 2018, to identify cardiologists who treat AF patients with acenocoumarol. A total of 300 cardiologists were selected and reported the number of AF acenocoumarol-treated patients during the past 12 months and the number of those who experienced a hemorrhagic event.

View Article and Find Full Text PDF

Background: Current European Guidelines suggest the use of cardiovascular risk categories and also recommend using high-intensity statins for patients with acute coronary syndromes (ACS).

Objective: We examined the risk of ACS patients prior to the event, as well as the overall use and intensity of statins.

Methods: We enrolled 687 ACS patients (mean age 63 years, 78% males).

View Article and Find Full Text PDF
Article Synopsis
  • The PHAETHON study aimed to recruit a representative cohort of acute coronary syndrome (ACS) patients in Greece to evaluate current treatment practices and patient outcomes amid recent advancements in therapy.
  • Conducted from May 2012 to February 2014, the study enrolled 800 ACS patients from diverse hospitals, tracking their health over a median of 189 days and assessing key outcomes like death and myocardial infarction.
  • Results showed a mean patient age of 62.7 years with most presenting as STEMI; complications occurred in 38% during hospitalization, and 12.6% faced significant events during follow-up, highlighting current management and prognostic challenges in ACS care.
View Article and Find Full Text PDF

Background: Prior studies conducted in Greece consistently indicate that dyslipidemia is suboptimally managed, while the burden of cardiovascular disease (CVD) and related risk factors is rising.

Methods: CHALLENGE was a multicenter, cross-sectional study carried out following the publication of guidelines advocating stricter low-density lipoprotein cholesterol (LDL-C) targets. It primarily aimed to depict LDL-C target attainment, and to assess the cardiovascular risk status and quality of life (QoL) of patients treated in a primary or secondary CVD prevention setting who had received any medical intervention for cardiovascular risk modification within 6months of enrollment.

View Article and Find Full Text PDF