Acute and Subchronic Oral Toxicity Study of Polyherbal Formulation Containing L., (Gaertn.) Roxb., Roxb., and Sol. ex. Maton in Rats.

The polyherbal formulation containing L., (Gaertn.) Roxb.

[Not Available].

The therapy for invasive candidiasis related to biofilms infection remains a difficult medical problem. To overcome this problem, efforts have been made to search for novel antibiofilm agents from various sources. This study investigated the in vitro antibiofilm activity of (1)-N-2-methoxybenzyl-1,10-phenanthrolinium bromide (FEN) against Candida albicans.

Antifungal Activity of (1)--2-Methoxybenzyl-1,10-phenanthrolinium Bromide against and Its Effects on Membrane Integrity.

Metal-based drugs, such as 1,10-phenanthroline, have demonstrated anticancer, antifungal and antiplasmodium activities. One of the 1,10-phenanthroline derivatives compounds (1)--2-methoxybenzyl-1,10-phenanthrolinium bromide (FEN), which has been demonstrated an inhibitory effect on the growth of spp. This study aimed to explore the antifungal activity of FEN and its effect on the membrane integrity of .