Isolated circinate balanitis successfully treated with topical tacrolimus.

Circinate balanitis, a common manifestation of reactive arthritis, is usually an associated finding seen with the clinical trial of arthritis, conjunctivitis, and urethritis. We hereby report a case of isolated circinate balanitis and its dermoscopic features in an adult patient. The patient responded successfully to treatment with topical tacrolimus 0.

Anticancer activity of , a rare and endemic species of holly in Northeast India, against murine lymphoma.

Purkay. is a lesser-known species of holly (family Aquifoliaceae) that is endemic to Northeast India. Designated as critically endangered, the plant is used in the treatments of bacterial infections, cancer, intestinal helminthiasis, tuberculosis, and viral infections.

Synthesis of fused-ring systems and diarylmethane flavonoids -quinone methide intermediates.

In this study, we investigated the ability of -quinone methide (-QM), an electron-poor diene, to undergo inverse electron-demand Diels-Alder (iEDDA) reaction with electron-rich dienophiles, resulting in fused-ring flavonoid systems. In addition, we explored the Michael-type addition using -QM and various nucleophiles, providing access to diarylmethane products. The cycloaddition reactions proceeded in a highly regioselective way, depending on the charge distribution of the reacting partners.

Simpson-Golabi-Behmel syndrome type 1 in a neonate with central hepatoblastoma.

We report a neonate evaluated for hepatomegaly during hospitalisation and was diagnosed to have hepatoblastoma, an uncommon childhood malignancy. The presence of dysmorphism, macrosomia and congenital heart defect led to the suspicion of congenital overgrowth conditions. The genetic evaluation revealed a pathogenic variant, conclusive of Simpson-Golabi-Behmel syndrome type 1 (SGBS1).

Self-Assembled Oligomers Facilitate Amino Acid-Driven CO Capture at the Air-Aqueous Interface.

Direct air capture of CO using amino acid absorbents, such as glycine or sarcosine, is constrained by the relatively slow mass transfer of CO through the air-aqueous interface. Our recent study showed a marked improvement in CO capture by introducing CO-permeable oligo-dimethylsiloxane (ODMS-MIM) oligomers with cationic (imidazolium, MIM) headgroups. In this work, we have employed all-atom molecular dynamics simulations in combination with subensemble analysis using network theory to provide a detailed molecular picture of the behavior of CO and the glycinate anions (Gly) at the ODMS-MIM decorated air-aqueous interfaces.