Publications by authors named "N Nakasato"

Objective: To evaluate the effects of changes in group delay from a click signal to a chirp signal on the 40-Hz Auditory Steady-State Response (ASSR) using magnetoencephalography (MEG).

Design: In this study, each participant was exposed to 10 chirp signals with gradually varying group delays from the CE chirp to the click at 60 dB nHL. The 40-Hz ASSR was measured using MEG and evaluated for amplitude and latency in the maximum signal channel at the click signal measured in each hemisphere.

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Article Synopsis
  • Recurring utterances (RUs) are a language symptom seen in severe aphasia, particularly in global or Broca's aphasia, but their underlying neural mechanisms are not well understood.
  • A novel technique called the super-selective Wada test (ssWada) was used on a 49-year-old man with drug-resistant epilepsy, targeting specific brain regions to induce Broca's aphasia with RUs through localized anesthetic administration.
  • This case highlights that RUs can occur without affecting the posterior language area or basal ganglia, suggesting ssWada's value in exploring brain-function connections related to language and cognition.
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Objective: This study aimed to clarify perceptions of the transition from pediatric to adult care for patients with childhood-onset epilepsy in Japan.

Methods: A qualitative descriptive study design was used. Semi-structured interviews were conducted with patients with childhood-onset epilepsy who had transitioned to adult care attending a tertiary hospital's adult outpatient care unit specializing in treating epilepsy.

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Magnetoencephalography (MEG) provides crucial information in diagnosing focal epilepsy. However, dipole estimation, a commonly used analysis method for MEG, can be time-consuming since it necessitates neurophysiologists to manually identify epileptic spikes. To reduce this burden, we developed the automatic detection of spikes using deep learning in single center.

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Article Synopsis
  • The study explored the complex decision-making process involved in disclosing epilepsy in the workplace, examining both the benefits and drawbacks of such disclosures.
  • Researchers analyzed data from 193 patients who underwent extensive assessments at a hospital's Epilepsy Monitoring Unit, focusing on various predictive factors related to the decision to disclose.
  • Results showed that 43.5% of patients chose to disclose their condition, with key influencing factors including experiences of discrimination and having witnessed their own seizures, as well as levels of enacted stigma.
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