The sleep-wake learning cycle is crucial for understanding human interaction with the environment and its relation to CNS diseases like epilepsy.
A study involved 178 epilepsy patients and healthy volunteers, examining the effects of prolonged sleep deprivation through clinical and EEG methods, while also observing brain changes in rats subjected to sleep deprivation.
The findings indicate that sleep deprivation leads to significant neuroplasticity impairments in the CNS, contributing to epilepsy development, suggesting further research on neuroplasticity modulators for treatment is necessary.