Oral Immunization of Mice with a Nonantibiotic Recombinant Coexpressing TsNd and gp43 Protein Vaccine Combined with a Murine Interleukin-33 Adjuvant.

Trichinellosis, a zoonotic disease transmitted through food and caused by , is a significant health concern worldwide. Therefore, developing a safe and effective vaccine to combat infection is essential. In this study, a nonantibiotic strain lacking the gene served as a live bacterial vector to deliver antigens to the host, creating a novel oral vaccine.

Inhibition mechanism of leukemia cells HL-60 by exopolysaccharides from Botryococcus braunii in response to high-concentration cobalt.

The influence of metal elements on the biomedical activity of microalgal exopolysaccharides (EPS) remains underexplored. This study examined the antitumor properties of Botryococcus braunii EPS under high cobalt conditions and the role of exogenous 3-indole acetic acid (IAA) in enhancing its activity. Results showed that IAA mitigated cobalt-induced inhibition of B.

The Application of Quantum Dots in Dental and Oral Medicine: A Scoping Review.

Objectives: To present an overview of quantum dots' (QDs) applications in dental and oral medicine, identify research gaps in existing relevant research, and provide insights into future research.

Data And Sources: An extensive electronic search was conducted across five databases from their inception to April 2024, complemented by a manual search. There were no restrictions regarding language or publication year.

Different Role of PET-CT Evaluation in Newly Diagnosed Follicular Lymphoma Upon Rituximab-Based Chemotherapy and Chemo-Free Immunotherapy.

Newly diagnosed follicular lymphoma (FL) patients usually received first-line rituximab-based immunochemotherapy (R-chemo). Recently, rituximab plus lenalidomide (R2) emerged as an alternative chemo-free immunotherapy. We performed a comparative analysis of positron emission tomography/computed tomography (PET/CT) in FL undergoing R-chemo or R2.

Liver transplantation in a boy with TFAM mutation associated mtDNA depletion syndrome.

Mitochondrial transcription factor A (TFAM) deficiency may cause mtDNA depletion syndrome, which manifests as neonatal liver failure or primary ovarian insufficiency, hearing loss, seizures, and intellectual disability. Treatment focusing on symptomatic management, and the clinical prognosis remains poor. Here, we describe a novel case of TFAM mutation presenting with progressive neonatal cholestasis, hypoglycemia and abnormal amino acid profiling.