Modification of the Hi-C Technology for Molecular Genetic Analysis of Formalin-Fixed Paraffin-Embedded Sections of Tumor Tissues.

Molecular genetic analysis of tumor tissues is the most important step towards understanding the mechanisms of cancer development; it is also necessary for the choice of targeted therapy. The Hi-C (high-throughput chromatin conformation capture) technology can be used to detect various types of genomic variants, including balanced chromosomal rearrangements, such as inversions and translocations. We propose a modification of the Hi-C method for the analysis of chromatin contacts in formalin-fixed paraffin-embedded (FFPE) sections of tumor tissues.

Autumn Migration of Greater Noctule Bat (Nyctalus Lasiopterus): through Countries and over Mountains to a New Migration Flight Record in Bats.

For the first time, using GPS-GSM trackers, long-term seasonal flights of greater noctule bat (Nyctalus lasiopterus) from summer habitats in Russia to wintering areas in Europe are recorded. One of the seasonal migratory flights is a record distance for bats (2515 km). The maximum daily flight was 445 km.

[Autotransplantation of a horizontally oriented fragment of the root of a removed tooth to preserve alveolar tissues].

The Aim Of Thestudy: To develop a method to contain atrophy of the alveolar bone and surrounding soft tissues in the area of many cortical teeth in the first 3 months after removal for subsequent installation of a dental implant.

Materials And Methods: A description of a method for containing atrophy of the alveolar bone and surrounding soft tissues after removal of the first molar of the mandible 3 months after tooth extraction is presented. The method consists in closing the mouth of the well with a horizontally oriented fragment of the root of the removed tooth with a preserved section of the ligamentous apparatus.

AB0 and rhesus blood groups as a risk factor for ARVI COVID-19.

The frequency of AB0 and Rhesus blood groups was studied in 12120 patients with COVID-19, 5180 convalescent plasma donors and 118801 healthy donors from Moscow, Smolensk, Yakutsk, Minsk and Gomel. In infected individuals, the frequency of blood group A was significantly higher than in uninfected individuals (41,54 % and 34,39 % respectively, p<0,05), and the frequency of blood group 0, on the contrary, was significantly lower (27,69 % and 36,71 %, p<0,05). The frequency of blood group A was particularly high among patients who died from ARVI COVID-19 - 45,51 % vs.