Management of COVID-19-Associated Acute Respiratory Distress Syndrome (ARDS) During Pregnancy Following In Vitro Fertilization (IVF).

Coronavirus disease 2019 (COVID-19), the disease caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is recognized for its heterogeneous clinical presentation, complex pathophysiology, and broad spectrum of manifestations. Obstetric patients have been a subject of considerable interest due to their potential vulnerability to more severe infection and adverse pregnancy outcomes, exemplified by this report of a 43-year-old pregnant female with severe COVID-19 infection and respiratory complications. This case report aims to contribute to the existing scientific knowledge by presenting a detailed clinical profile of a patient with COVID-19 who achieved pregnancy through in vitro fertilization (IVF) and discussing the management and outcomes of the infection.

Epithelial-Mesenchymal Transition: A Fundamental Cellular and Microenvironmental Process in Benign and Malignant Prostate Pathologies.

Epithelial-mesenchymal transition (EMT) is a crucial and fundamental mechanism in many cellular processes, beginning with embryogenesis via tissue remodulation and wound healing, and plays a vital role in tumorigenesis and metastasis formation. EMT is a complex process that involves many transcription factors and genes that enable the tumor cell to leave the primary location, invade the basement membrane, and send metastasis to other tissues. Moreover, it may help the tumor avoid the immune system and establish radioresistance and chemoresistance.

EFFECT OF AGE AT DIAGNOSIS ON THE PROGNOSES IN FEMALE BREAST CANCER PATIENTS IN GEORGIA.

The aim of the study was to describe prognostic factors of Breast Cancer (BC) survival in relation to patient's age at diagnosis. Cox proportional hazard regression model was constructed. All women aged ≤80 years, diagnosed from 2006 to 2015 with invasive breast cancer, and included in the national cancer registry database, were eligible for inclusion in the analysis.

EFFECT OF SELECTED PROGNOSTIC AND RISK FACTORS ON SURVIVAL OF WOMEN WITH BREAST CANCER IN GEORGIA.

According to the population-based cancer registry data in Georgia, the incidence rate of breast cancer per 100000 women was 90.6 in 2016. The aim of this study is to explore the effects of risk and prognosis factors on survival of female invasive breast cancer patients in Georgia.

FACTORS AFFECTING SURVIVAL OF WOMEN DIAGNOSED WITH BREAST CANCER IN GEORGIA.

Breast cancer is the most frequently diagnosed cancer in women worldwide with nearly 2.4 million new cases diagnosed in 2015, In Georgia survival from breast cancer is lower than in many developing countries. The goal of the study was to identify predictors for low survival of disease in the country.