[Creation and use of a liquid substance based on association of petroleum-oxidizing bacteria].

An association of four bacterial strains with high oil-oxidizing and bioemulsifying activities, psychrophilicity, resistance to chemical pollutants, and lack of pathogenicity was selected from a collection of natural oil-oxidizing microorganisms. A new liquid preparation containing stabilizers and preservatives that maintain the cell viability and oil-oxidizing activity during long-term storage was developed. A field experiment in oil-polluted sod-podzol and clay sand soils demonstrated that this preparation accelerated the biodegradation of oil and its individual fractions, especially in the presence of mineral and organic fertilizers.

[The 25th anniversary of the State Scientific Research Center for Applied Microbiology. Achievements and prospects].

State Research Center for Applied Microbiology was founded in 1974 for accelerated development of molecular biology and molecular genetics in the USSR and rapid practical application of achievements of these sciences to economy and medicine.

[Monitoring of life-threatening infection pathogens in relation to the problem of prediction of critical situations].

The epidemic situation in the context of many infectious diseases caused by bacteria is presently assessed as being poor in Russia and other countries. The spectrum of the pathogens that can deteriorate epidemic well-being is highly wide. The epidemic situation in terms of many infectious diseases, including those caused by such causative agents as Bacillus anthracis, Vibrio cholerae, Yersinia pestis, Francisella tularensis and others may deteriorate due to the emergence of their modified forms owing to their specific variability.

[Stable expression of heterologous proteins in salmonella: problems and approaches to their designing].

Live attenuated Salmonella vaccines may be used as carriers of heterologous antigens. The optimum expression system for each heterologous antigen requires to be established on an individual basis. This will ensure that the antigen in question is produced at appropriate levels and in the correctly folded conformation.