[UltrastructuraL analysis of the action of levorin on Entamoeba].

The paper is concerned with investigation of the nature of ultrastructural alterations in Entamoeba moshkovski under the levorin effect. The studies showed that under the effect of levorin there appeared in the Entamoeba cultures diverse types of cells having chiefly the following ultrastructural alterations: a higher number and size of cytoplasmic vacuoles, lower density of the cytoplasm granular component, not intact nuclear and plasmatic membranes and cell cytolysis. Analysis of the experimental results suggested that the amebicidal effect of levorin on Entamoeba was mainly associated with its membranotropic properties.

[Effect of levorin and its combination with a modifying factor on lipid peroxidation in Crithidia oncopelti].

It was shown earlier by the authors that in the presence of sodium acetate as a modifier of C. oncopelti reaction to levorin, a polyenic antibiotic sensitivity of this organism to the antibiotic increased. At the same time there were observed changes in the ratio of the lipids and fatty acids of the total lipid fraction of C.

[Effect of levorin and its combination with a modifying factor on the fatty acid composition of Crithidia oncopelti lipids].

It was shown by us earlier that the sensitivity of Crithidia oncopelti to levorin, a polyene antibiotic, increased in the presence of sodium acetate as a modifying factor. A simultaneous change in the ratio of C. oncopelti structural lipids was also observed.