The authors present data on the protective effect of newborn rabbits pancreatic islet cell culture xenotransplantation of Langerhans' islet beta-cells of rats with alloxan diabetes. This effect was the most marked in rats fed diets with normal or increased protein content. The authors discuss a possible stimulating effect of rabbit islet cell culture xenotransplantation on regeneration processes in recipient rat pancreatic islets.
View Article and Find Full Text PDFThe pancreas from bovine fetuses of 27-35 cm crown-rump length were used as a source of islet cell cultures. Pancreatic tissue was treated by collagenase, filtered through the metal sieve and incubated in MEM for 24 h. Using this method, cultures similar to so-called pseudo-islets were obtained.
View Article and Find Full Text PDFThe authors describe the effect of intramuscular human fetal pancreatic islet cell (IC) culture transplantation on the clinical course of proliferative diabetic retinopathy (PDR). Four patients with the preterminal stage of PDR were followed-up no less than 2 yrs. after transplantation.
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