[Analysis of the causes of cancer negligence and low survival in the patients with malignant neoplasms of ENT and oral cavity in the city of Moscow].

The objective of the present study was to elucidate the causes of late detection of malignant neoplasms of ENT and oral cavity and low survival of the patents with these tumours in Moscow. The secondary objective was to elaborate the organizational measures for reducing the level of negligence and mortality from these malignancies among the city population. It was shown that the main cause behind the negligence is the late application of the patients for the medical assistance.

[TiO2-DNA nanocomposites capable of penetrating into cells].

Methods of noncovalent immobilization of DNA fragments onto titanium dioxide nanoparticles (TiO2) were developed, which led to TiO2-DNA nanocomposites capable of penetrating through cell membranes. TiO2 nanoparticles of different forms (amorphous, anatase, brookit) with enhanced agglomeration stability were synthesized. The particles were characterized by X-ray diffraction, small angle X-ray scattering, infrared spectroscopy and atomic force microscopy.

[Prophylactic medical examination of patients with head and neck tumours in Moscow--continuity of patients' care provided by oncologists and general practitioners].

The primary objective of prophylactic medical examination of oncological patients is reduction of mortality and improvement of the quality of life. Activities of the Department of Head and Neck Tumours of No 1 Oncological Clinical Dispensary are focused on dynamic follow-up of treated patients for early identification of continued tumour growth, diagnosis of relapses and metastases. Compliance with the schedule of control examination in the post-treatment period facilitates early identification of continued tumour growth, diagnosis of relapses and metastases.

[Delayed results of the treatment of patients with laryngeal cancer in Moscow].

The objective of the present study was to analysis results of the follow-up survey involving 1,532 patients with laryngeal cancer residing in Moscow for the period from 1999 till 2005. The five-year survival rates among the patients treated in otolaringological departments of general medical care settings (12.6%) and in specialized oncological centers of Moscow (87.

[Principles of early diagnosis of malignant neoplasms in ENT organs].

According to Moscow city Oncological Dispensary, the number of patients with malignant neoplasms of ENT organs has increased during the last 5 years. In 79-84% of the patients the diseases is diagnosed at stage III-V which leads to rather poor results of treatment. Results of analysis of causes for late diagnosis of ENT neoplasms point out to the necessity to raise oncologic alertness among ambulatory physicians.