Possibilities of transmission electron microscopy in assessing the quality of bacterial cells and microbial population.

Determination of changes in the morphostructure of microorganisms under the influence of antibiotics, disinfectants, biocins, physical and chemical agents is carried out using the method of visualization of ultrathin sections in a transmission electron microscope. The aim is to develop methodological techniques for express preparation and visualization of the ultrastructure of bacteria in a transmission electron microscope to detect structural damage to cells and assess the quality of the microbial population. A technique of accelerated sample preparation for visualization of the fine structure of bacteria and diagnosis of structural damage to cells in a transmission electron microscope has been developed.

[Implication of specialized sanatoria in the improvement of care to patients with ocular tuberculosis at the present stage].

A total of 6230 case histories and the data of annual reports over the past 7 years were examined. A therapeutic-and-diagnostic process continues to be improved under the present-day conditions. Patients admitted to the sanatorium for the inadequately substantiated etiology of ocular tuberculosis underwent an additional differential diagnostic study.