Publications by authors named "N N Koberskaia"

The efficacy of cerebrolysin has been studied in 40 patients with cerebral vascular insufficiency and moderate cognitive impairment. The treatment in dosage of 10 ml cerebrolysin per 200 ml of physiological solution (20 intravenous injections daily) was effective in this group of patients. The course therapy with cerebrolysin reduced memory and attention disturbances improving the total cognitive status of patients.

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Aim: To evaluate effects of cerebrolysin on cognitive functions in patients with mild cognitive impairment of vascular genesis.

Material And Methods: The examination covered 43 patients aged 40 to 80 years with mild cognitive impairment. We used Tinetti scale for assessment of dynamics in postural disorders; neuropsychological examination was based on Short Scale of Psychic Status Assessment, Mattis Dementia Scale, ADAS- Cog scale, digit test and other tests.

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Neurodegenerative diseases accompanied by cognitive impairment (dementia with Levy's bodies--DLB and Alzheimer's disease--AD) and others) are becoming more widespread due to increasing population life expectancy. The paper addresses use of cognitive event-related potential P300 to verbal and nonverbal stimuli with an assessment of interhemispheric asymmetry and topographic distribution of P300 in patients with DLB and AD comparied to age-matched healthy controls. Specific alterations of P300 amplitude and latency suggest a use of cognitive event-related potential P300 in differential diagnosis of DLB and AD.

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