[Interrelationship between the chain length of poly-L-lysine and the degree of protection of polyribonucleotide interferon inducers from human blood nucleases].

The action of the human total blood serum on polynucleotide interferon inducers, larifan and ridostin (natural double-stranded RNAs) and poly(I).poly(C) (a double-stranded complex of synthetic polyribonucleotides) used both in the free state and in the state shielded with poly-L-lysine was studied. The rate of the accumulation of the acid soluble products was compared with the residual interferon-inducing activity in mice.

[Resistance of natural and synthetic polyribonucleotide inducers of interferon to human blood ribonucleases].

The resistance of polyribonucleotide inductors of interferon to blood ribonucleases was studied. Blood resistance of larifan and ridostin in the free and shielded state as well as that of the complexes of poly(I)-poly(C) and poly(G)-poly(C) were also investigated. A protective action of polylysine against the inductors was detected which, in case it had no effect on the biological activity of the drugs, could provide its recommendation as a compound for shielding the inductors.

[Value of rheovasography and thermography in the diagnosis of varicose veins of the legs in the practice of expert evaluation of work capacity].

The article deals with the problems of using such new modern diagnostic methods as rheography and thermography in objective assessment of the degree of functional disorders in patients with lower limb varicosis. The authors describe the examination method, the necessary apparatus, and the evaluation of the qualitative and quantitative parameters on the basis of the information obtain. The results of the examination provide the possibility to determine exactly the degree of chronic venous insufficiency, judge the condition of the valvar apparatus of the veins, appraise the compensatory possibilities of the vascular wall and the clinical prognosis, and consequently, to solve more objectively the questions of expert medical assessment of the working capacity.