[Neurotrophic regulation of the restorative processes in muscle autografts in vertebrates].

In frogs, tortoises and rats autotransplantation of the whole gastrocnemius muscle has been performed into its own bed at sewing the nerve to the autotransplant and at its denervation. Fragments of the skeletal muscles are also transplanted into the brain and into the spinal cord in frogs and rats. By means of light and electron microscopy, restorative processes are studied in the transplanted muscles.

[Effect of the survival of xenografts in animals].

A method of free xenotransplantation of skeletal muscles (from rat donors) to another species (mouse, hamster or guinea pig) has been elaborated. It has been shown that the muscle (gastrocnemius) of the donor animal acquires the property to survive and develop when wrapped in a cellophane film. The muscle should be kept wrapped in a cellophane film for up to 330 days.

[Secondary development of minced muscle tissue of amphibia during transplantation and cultivation in diffusion chambers].

The development of the skeletal muscular tissue from the frog Rana ridibunda was studied under autotransplantation and cultivation in diffusion chambers of the minced gastrocnemius muscle implanted intraperitoneally to other species of the same family. The material was examined by light or scanning electron microscopy. In both series of experiments, the muscular tissue from adult frogs retained its viability and reconstructive activity for a long time.

[Role of neuromuscular connections in the morphogenetic process occurring in transplanted amphibian muscles].

Totally excized gastrocnemial muscles of the frog (Rana ridibunda) were replanted into their own matrix. The transplants were innervated by the tibial nerve which was specially brought to them or remained denervated. Reinnervation of the transplanted muscles started after 2 months, their contractility being recorded by the 4th month.