Publications by authors named "N Munro"

Climate change is apparent. Temperatures are rising. Floods are more frequent and devastating.

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Background: Patients who do not achieve positive outcomes with custom ethylene-vinyl-acetate (EVA) foot orthoses will often be escalated to other services for treatment, which may include surgery.

Objective: This study aimed to explore the effectiveness of custom hard-shell 3D-printed foot orthoses for patients who did not respond to treatment with custom EVA foot orthoses and were being considered for treatment escalation.

Design: An eight-week clinical evaluation and a two-year review of relevant medical records.

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Article Synopsis
  • PAMAM dendrimers, particularly the generation 4 (G4) version with a fully amine surface, are highly toxic to cells, prompting researchers to modify them for better biocompatibility by introducing neutral hydroxyl groups.
  • The modified G4-90/10 dendrimers, with a surface changing to 10% amine and 90% hydroxyl, show less toxicity and effective cellular uptake in various cell types, including neurons and stem cells.
  • Studies demonstrate that these dendrimers migrate within the brain after injection, with the G4 variety exhibiting more extensive movement patterns compared to G1 dendrimers, particularly in the anterior, posterior, and lateral directions, along with unique projections to cortical areas.
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Purpose: The purpose of this study was to describe the speech production, speech perception, vocabulary, and word learning abilities of lexically precocious 4-year-old children with phonological impairment, in an effort to better understand the underlying nature of phonological impairment in children.

Method: Using a case series approach, we identified four children with phonological impairment and precocious vocabulary abilities. Each child completed routine speech production and vocabulary assessments, as well as experimental speech perception and word learning tasks.

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