Publications by authors named "N Munfakh"
Article Synopsis
- The PROSE trial aimed to compare the On-X mechanical prosthesis with the St Jude Medical mechanical prosthesis for thromboembolic complications.
- The study involved 855 subjects across 28 centers from 2003 to 2016 and found no significant differences in thromboembolism or mortality rates between the two prostheses at the 5-year mark.
- Notable differences were observed in valve thrombosis occurrences based on valve position and between Western and Developing populations, with Developing populations experiencing more complications, particularly in the mitral valve position.
Background: As of 2019, pericardial closure was performed in only a small portion of the over 320,000 cardiac surgeries performed annually. However, evidence regarding the benefits of pericardial closure or reconstruction has been accruing, particularly with the publication of the RECON study in 2019. Methods: This group of authors convened to try to arrive at consensus expert opinion regarding pericardial reconstruction.
View Article and Find Full Text PDFObjectives: The PROSE trial purpose is to investigate whether the incidence of thromboembolic-related complications is reduced with a current generation mechanical prosthesis (On-X Life Technologies/CryoLife Inc.-On-X) compared with a previous generation mechanical prosthesis (St Jude Medical-SJM). The primary purpose of the initial report is to document the preoperative demographics, and the preoperative and operative risk factors by individual prosthesis and by Western and Developing populations.
View Article and Find Full Text PDFArticle Synopsis
- The study examines the impact of surgeon experience on outcomes in reoperative cardiac surgery over more than three decades.
- It finds that standardized mortality ratios were highest for surgeons in the early (0-4 years) and late (29-39 years) stages of their careers, meaning these groups had worse outcomes.
- Conversely, surgeons with 9-17 years of experience had the best outcomes, indicating that as surgeons gain experience, patient outcomes improve initially but may decline again as they age.
Objective: Valve selection in dialysis-dependent patients can be difficult because long-term survival is diminished and bleeding risks during anticoagulation treatment are greater in patients with renal failure. In this study we analyzed long-term outcomes of dialysis-dependent patients who underwent valve replacement to help guide optimal prosthetic valve type selection.
Methods: Dialysis-dependent patients who underwent aortic and/or mitral valve replacement at 3 institutions over 20 years were examined.