Publications by authors named "N Mitra"

Thalassemia is a hematological disorder caused by mutations in the hemoglobin gene, often necessitating regular blood transfusions. These frequent transfusions exert continuous pressure on patients' immune systems. Despite extensive research on the hematological aspects of thalassemia, few studies have explored the immune status of these patients.

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Importance: Taxation of sweetened beverages is a proposed strategy to reduce excess sugar consumption. The association of such taxes with health outcomes is not well studied. Philadelphia, Pennsylvania, is the largest US city with a beverage tax.

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Background: Sweetened beverage taxes are associated with large decreases in sugar-sweetened beverage sales, but their effects on weight outcomes are unclear. We examined associations of the 2017 Philadelphia beverage tax with changes in adult weight outcomes.

Methods: We obtained electronic health record data on adults 18-65 years old in Philadelphia (intervention) and other areas of Pennsylvania and New Jersey (control) from 2014 to 2019.

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Background: Progranulin (PGRN), also identified as Precursor cell-derived growth factor (PCDGF), is a glycoprotein that is expressed and released ubiquitously. PGRN is plays a crucial role in regulating cell proliferation, differentiation, and pathological pathways. PGRN overexpression has been noted in many cancers and plays an important role in wound healing.

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Article Synopsis
  • The study explores the complex causes of seborrhoeic dermatitis (SebD), involving skin microbes, immunity, and genetics, noting two types: infantile and later-onset SebD.
  • Researchers analyzed over a million children from a UK medical database to see if a mother's history of SebD affects the risk of their children developing either form of the condition.
  • Findings indicate that maternal SebD is linked to a higher risk of children developing both ISebD and childhood-onset SebD, but children with ISebD are not likely to develop the later form.
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