Prerequisites for Stabilizing Long-Range Synergistic Interactions among -, -, and -Residues in Coiled Coils.

Coiled coils are among the most abundant tertiary and quaternary structures found in proteins. A growing body of evidence suggests that long-range synergistic interactions among solvent-exposed residues can contribute substantially to coiled-coil conformational stability, but our understanding of the key sequence and structural prerequisites of this effect is still developing. Here, we show that the strength of synergistic interaction involving a -position Glu (), an -position Tyr ( + 4), and a -position Lys ( + 8) depends on the identity of the -position residue, the length and stability of the coiled coil, and its oligomerization stoichiometry/surface accessibility.

Medical Diagnoses in a University Athlete Training Room Clinic.

Introduction: Approximately 560 000 student-athletes participate in university athletic programs every year. These athletes develop a variety of medical injuries and illnesses during their time at the university. There is currently a paucity of data with regarding medical encounters in a dedicated university athlete training room clinic.

INVESTIGATION OF PRIMARY AND SECOND ANTERIOR CRUCIATE LIGAMENT TEARS USING A GEOGRAPHIC DATABASE.

Background: The incidence of anterior cruciate ligament (ACL) injuries has been estimated at 1 in 3500 individuals in the literature. Second ACL tears represent 7-14% of all ACL tears. The location of ACL tears has been noted to be primarily proximal.

Comparison of experiences of stress and coping between young people at risk of psychosis and a non-clinical cohort.

Background: Although the experience of stress and associated coping responses are thought to play a role in the onset of schizophrenia and other psychotic disorders, there is little empirical evidence to support such a relationship. The relatively recent development of validated and reliable criteria for identifying young people at "ultra" high-risk (UHR) of psychosis has enabled the process of illness onset to be studied more closely than was previously possible.

Method: This longitudinal study compared the experiences of stress and coping between a UHR cohort (N=143) and a healthy comparison group (HC group, N=32).

Latent fingermark visualisation using reduced-pressure sublimation of copper phthalocyanine.

The sublimation of copper phthalocyanine (CuPc) at a temperature of 400°C under conditions of reduced pressure is shown to be an effective method of developing latent fingermarks on certain types of surface. Preliminary experiments on a limited selection of surfaces including paper, plastic and ceramic tiles were carried out using a simple apparatus consisting of a vacuum desiccator and a resistive heater. CuPc from the gas phase condenses preferentially on fingermark deposits, revealing deep blue patterns with excellent ridge detail clarity on light coloured surfaces.