Publications by authors named "N Mattsson"
Quality of Sexual Life Before and After Pelvic Organ Prolapse Surgery.
Urogynecology (Phila)
October 2024
Importance: Although surgery for pelvic organ prolapse (POP) is generally associated with an improvement in sexual function, knowledge on specific changes is limited.
Objectives: The aim of this study was to describe and compare changes in sexual activity and function during a 5-year follow-up period after POP surgery.
Study Design: This was a nationwide cohort study of 3,515 women operated on for POP in 2015 in Finland.
Article Synopsis
- - This study evaluated the impact of pelvic organ prolapse (POP) surgery on stress urinary incontinence (SUI), focusing on symptom changes, follow-up procedures, and factors influencing outcomes in patients without prior SUI surgery.
- - Out of 2,677 surgeries analyzed, about 50% initially reported SUI symptoms, with significant improvements noted post-surgery, though 20% developed new SUI symptoms afterwards.
- - Key findings showed that higher baseline symptom severity raised the likelihood of persistent SUI, while certain factors, like age and prior urgency urinary incontinence, were linked to developing new SUI symptoms following the surgery.
Background: Even though surgery generally improves sexual function and alleviates dyspareunia related to pelvic organ prolapse (POP), knowledge of the long-term effects is scarce.
Objective: To describe changes in sexual activity and dyspareunia rates after POP surgery and to identify potential risk factors for the occurrence of dyspareunia.
Design Setting And Participants: This was a prospective longitudinal cohort study of women aged over 18 yr undergoing POP surgery in Finland during 2015.
Background: In experimental animal studies, exposure to general anesthesia in early childhood may results in changes in infant brain morphology and behavior, potentially leading to the development of autistic behaviors in the long-term. However, in clinical studies the role of exposure to general anesthesia in early childhood and the risk of autism is unknown.
Methods: This is a population-based cohort study including all children aged 0-5 years of age exposed to general anesthesia between 2001 and 2014 and a corresponding matched population without such an exposure.
Article Synopsis
- The study investigates the prevalence of amyloid aggregation, a key feature of Alzheimer's disease, in individuals with varying cognitive statuses, including those with normal cognition and who have clinical AD dementia.
- It analyzes how factors like age, sex, educational background, and the method of detecting amyloid (CSF or PET scans) influence the prevalence estimates.
- Data were collected from 85 study cohorts between 2013 and 2020, using a systematic approach to categorize amyloid measurements as normal or abnormal.