Publications by authors named "N Mashima"
Introduction: Immune checkpoint inhibitors (ICIs) are increasingly being used in the treatment of advanced metastatic and immunogenic cancers. However, these therapies could cause immune-related adverse events (irAEs), which require high-dose glucocorticoid administration.
Case Report: A 52-year-old man with metastatic renal cell carcinoma received ICI therapy.
Article Synopsis
- This study investigates the time from diagnosis to surgery for osteonecrosis of the femoral head (ONFH) and factors affecting its severity among 2074 cases in Japan from 1997 to 2018.
- The median time to surgery was found to be 9 months, influenced by whether the patient used alcohol or corticosteroids, and the stage of joint destruction at diagnosis.
- The study highlights that a large proportion of patients remain untreated for extended periods, but surgery was performed within 9 months for more than half of the patients, indicating the disease's serious impact.
Purpose: The aims of this study were to 1) assess femoral head translation during weight-bearing in symptomatic developmental dysplasia of the hip (DDH) and 2) compare it between borderline DDH and definite DDH.
Methods: The study included four individuals with borderline DDH and nine with definite DDH, scheduled for periacetabular osteotomy. Anteroposterior X-ray images of the hip joint were obtained in the standing position, and computed tomography images of the pelvis were obtained in the supine position.
Background: Pre-treatment albumin-bilirubin grade is a useful biomarker for predicting prognosis in patients receiving immune checkpoint inhibitors for advanced malignancies. We evaluated the prognostic impact of pre-treatment albumin-bilirubin grade in patients receiving pembrolizumab for metastatic urothelial carcinoma.
Methods: In this multicenter retrospective study, we calculated pre-treatment albumin-bilirubin scores of 96 patients who received pembrolizumab for metastatic urothelial carcinoma between January 2018 and March 2022.
Objective: To extend life expectancy after surgery, patients with hip fractures need to improve their mobility quickly through postoperative rehabilitation. Voluntary hip joint motion supported by the hybrid assistive limb (HAL) lumbar type, an exoskeleton robot suit characterized by its ability to detect the wearer's intentions through the bioelectrical signals and assist hip extension motions at an optimal timing, may be effective to improve mobility in patients with hip joint dysfunction after surgery. We aimed to introduce rehabilitation using the HAL lumbar type in the early period after hip fracture surgery.
View Article and Find Full Text PDF