Publications by authors named "N Martin-Silva"
Article Synopsis
- - The study investigates how serum levels of ceruloplasmin, an inhibitor of myeloperoxidase, affect the prognosis of patients with anti-MPO antibody-positive anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV).
- - It analyzed data from 92 patients, revealing that those with lower ceruloplasmin levels had a significantly higher death rate (40% vs. 12%) during a median follow-up of 40 months.
- - The findings suggest that ceruloplasmin levels at diagnosis could be an important marker for survival in patients with anti-MPO AAV, while similar analyses in anti-PR3 antibody patients showed no differences.
Seventy-seven patients with antiphospholipid syndrome were tested for autoantibodies against C1q, C3, FB, FH, and C4bp. Fifty-seven patients had at least one anti-complement antibody. IgM anti-FH positivity was associated with thrombosis when anti-C3 and anti-FB were, negatively or positively, associated with various noncriteria manifestations of antiphospholipid syndrome.
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- The study aimed to identify factors contributing to the progression of aortic dilations in patients with giant cell arteritis (GCA).
- Among 47 analyzed patients, 28% experienced fast-progressive aortic dilations, while 34% had slow-progressive and 38% were not progressive, with no significant differences in baseline characteristics across these groups.
- Fast-progressive patients were more likely to have atheromatous disease and used statins and antiplatelet agents more frequently; inflammation in the aorta was linked to dilation in the majority of patients with GCA-related aortitis.
Facial and neckline telangiectasias have an underestimated yet important impact on quality of life of patients with systemic scleroderma (SSc). This monocentric, prospective, open-label, intra-patient comparative study was conducted in 21 consecutive patients with SSc. Patients underwent 4 sessions of PDL 8 weeks apart.
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