Publications by authors named "N Markou"
Article Synopsis
- Researchers classified sepsis into four clinical phenotypes using a simplified algorithm based on six admission parameters in a study involving 1498 patients, including those with bacterial sepsis and severe COVID-19.
- The analysis found distinct characteristics and outcomes for the phenotypes, with Phenotype α showing low mortality risk and Phenotype δ having the highest mortality.
- The study concludes that this phenotyping method is effective for predicting outcomes in both bacterial sepsis and severe COVID-19, suggesting it could have important prognostic applications.
Objectives: It is suggested that sepsis may be classified into four clinical phenotypes, using an algorithm employing 29 admission parameters. We applied a simplified phenotyping algorithm among patients with bacterial sepsis and severe COVID-19 and assessed characteristics and outcomes of the derived phenotypes.
Design: Retrospective analysis of data from prospective clinical studies.
Article Synopsis
- The COVID-19 pandemic resulted in a notable increase in invasive fungal infections among critically ill patients, leading to new diagnostic and treatment challenges.
- This review specifically examines the rise of mold infections caused by certain species in COVID-19 patients, detailing their incidence, causes, and management.
- The study emphasizes that traditional risk factors for these infections were often overlooked in COVID-19 cases, resulting in poorer outcomes for patients with these co-infections compared to those without.
Article Synopsis
- The study aimed to demonstrate the use of a new computer-assisted surgical guide for periodontal surgery in patients with severe gingival enlargement, specifically hereditary gingival fibromatosis.
- A comprehensive treatment plan included nonsurgical therapy, surgical intervention, and regular maintenance, with a custom surgical guide designed from intraoral scans and CBCT images to improve the surgical process.
- Results showed that the guide enhanced the precision of gingivectomy, making the surgery more efficient and leading to better outcomes in managing soft tissue in affected patients.
Article Synopsis
- * Invasive infections are tied more to procedures like mechanical ventilation than to traditional risk factors seen in other patients, highlighting the unique challenges posed by COVID-19.
- * The review emphasizes the concerning rise in fluconazole-resistant fungal strains and how these co-infections significantly worsen patient outcomes, increasing morbidity and mortality rates.