Publications by authors named "N Manocchio"

Osteoarthritis (OA) is a disabling disease that causes pain and functional limitation. OA symptoms can be treated with intra-articular injections of anti-inflammatory, viscosupplementary, or viscoinductive products. Non-responders to these approaches have limited options, often surgical (e.

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  • * The relationship between muscle force and bone health is crucial as decreased muscle activity can lead to bone loss, a concern not yet fully studied in clinical settings.
  • * The review examines how the use of BTX can disrupt the balance between muscles and bones, potentially leading to conditions like osteopenia and increased bone resorption, especially in instances such as spinal cord injuries.
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Article Synopsis
  • The review looked at how some common drugs used in joint injections might harm cartilage in the body.
  • Researchers found 185 articles, read many of them, and included 65 studies that met their rules.
  • They discovered that some drugs like corticosteroids and certain local painkillers could be risky, while hyaluronic acid seems safer; more research is needed for other treatments like platelet-rich plasma.
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Chronic low back pain (cLBP) is a major cause of disability and healthcare expenditure worldwide. Its prevalence is increasing globally from somatic and psychosocial factors. While non-pharmacological management, and in particular physiotherapy, has been recommended as a first-line treatment for cLBP, it is not clear what type of physiotherapeutic approach is the most effective in terms of pain reduction and function improvement.

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Recent studies underscore the intricate relationship between cognitive and motor impairments in Multiple Sclerosis (MS), often exacerbated by CNS damage compromising neural connections. These cognitive-motor deficits contribute to reduced efficiency in daily activities and heightened risks of falls and accidents. The combination of challenging cognitive-motor training in a more ecological setting could improve cognitive functions in people with MS (PwMS).

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