Modulation of Transaminase Activity by Encapsulation in Temperature-Sensitive Poly(N-acryloyl glycinamide) Hydrogels.

Smart hydrogels hold much potential for biocatalysis, not only for the immobilization of enzymes, but also for the control of enzyme activity. We investigated upper critical solution temperature-type poly N-acryloyl glycinamide (pNAGA) hydrogels as a smart matrix for the amine transaminase from Bacillus megaterium (BmTA). Physical entrapment of BmTA in pNAGA hydrogels results in high immobilization efficiency (>89 %) and high activity (97 %).

Are the Parameters of Novel Two-Point Force-Velocity Model Generalizable in Leg Muscles?

The two-point force-velocity model allows the assessment of the muscle mechanical capacities in fast, almost fatigue-free conditions. The aim of this study was to investigate the concurrent validity of the two-point parameters with directly measured force and power and to examine the generalization of the two-point parameters across the different functional movement tests of leg muscles. Twelve physically active participants were tested performing three functional lower limb maximal tests under two different magnitudes of loads: countermovement jumps, maximal cycling sprint, and maximal force under isokinetic conditions of the knee extensors.

Assessment of the two-point method applied in field conditions for routine testing of muscle mechanical capacities in a leg cycle ergometer.

Purpose: The aim of this study was to compare the reliability and magnitude of the force-velocity (F-V) relationship parameters [maximum force (F0), maximum velocity (V0), F-V slope, and maximum power (P0)] obtained through the application of only two loads (i.e., two-point method) vs.

[Assessment of required resources for implementation of national breast cancer screening program in Serbia].

Introduction: High values of standardized mortality and morbidity rates of standardized cancer mortality in Serbia, especially colorectal, cervical and breast cancer led to creation of national programs for their early detection and engagement of the international support for their implementation.

Objective: Assessment of required resources (time, personnel, financial) to implement the National program for screening of breast cancer in the Republic of Serbia.

Methods: Three possible scenarios have been prepared (optimistic, realistic and pessimistic) based on the expected coverage by screening of women aged 45 to 69 years, and time, personnel and financial feasibility estimates were made for a two-year screening cycle.