Progerin can induce DNA damage in the absence of global changes in replication or cell proliferation.

Hutchinson-Gilford Progeria Syndrome (HGPS) is a rare genetic condition characterized by features of accelerated aging, and individuals with HGPS seldom live beyond their mid-teens. The syndrome is commonly caused by a point mutation in the LMNA gene which codes for lamin A and its splice variant lamin C, components of the nuclear lamina. The mutation causing HGPS leads to production of a truncated, farnesylated form of lamin A referred to as "progerin.

Development of Sodium-Lithium-Manganese-Cobalt Oxide with B Doping or B/F Dual Doping as Cathode Electrode Materials for Sodium-Ion Batteries.

The abundance of raw materials is a significant advantage that positions sodium-ion batteries (SIBs) as a promising energy storage solution for the future. However, the low cycle efficiency and poor rate capacity of cathode materials have hindered the commercialization of SIBs, prompting extensive research efforts to address these challenges. Ion doping into the material structure is considered to be an effective, simple, and scalable approach to enhancing the electrical performance of cathode materials.

Electric field enhances the electronic and diffusion properties of penta-graphene nanoribbon anodes in lithium-ion batteries.

Enhancement of the ionic conductivity and reduction of diffusion barriers of lithium-ion batteries are crucial for improving the performance of the fast-growing energy storage devices. Recently, the fast-charging capability of commercial-like lithium-ion anodes with the smallest modification of the current manufacturing technology has been of great interest. We used first principles methods computations with density functional theory and the climbing image-nudged elastic band method to evaluate the impact of an external electric field on the stability, electronic band gap, ionic conductivity, and lithium-ion diffusion coefficient of penta-graphene nanoribbons upon lithium adsorption.