Publications by authors named "N Maggi Kelly"
Increasingly, people attending HIV services are requesting long-acting injectable (LAI) antiretroviral treatment (ART). However, without HIV RNA resistance-associated mutation results, individuals are considered unsuitable for LAI ART. We present our experience of sequencing proviral HIV DNA in 30 individuals to inform suitability for LAI ART, of whom 23 were considered suitable.
View Article and Find Full Text PDFEvaluating utility of allergy testing in management of nasal obstruction following inferior turbinate reduction.
Int J Pediatr Otorhinolaryngol
November 2024
Article Synopsis
- Allergic rhinitis (AR) is a prevalent chronic condition in children, often leading to nasal obstruction caused by inferior turbinate hypertrophy (ITH), which may require inferior turbinate reduction (ITR) surgery.
- The study reviewed data from 297 pediatric patients who underwent ITR in 2015, finding that 20.9% experienced recurrent nasal obstruction and 5.4% needed revision surgery afterward.
- Allergy testing was performed on about 37.7% of the patients, revealing no significant differences in recurrence or revision rates between those with positive and negative allergy test results.
Article Synopsis
- Sleep deprivation is linked to significant health risks, including an increased likelihood of influenza, particularly following acute sleep deprivation events (ASDEs) identified in a large population study.
- The study used data from Fitbit users to analyze sleep patterns and health outcomes, revealing a correlation between political/non-political events and instances of decreased sleep.
- Genetic factors related to sleep duration were found to influence both the severity of sleep deprivation and the risk of subsequent health issues, emphasizing the need for awareness of health impacts during major national events.
Article Synopsis
- The study highlights how underrepresentation in clinical genomics research diminishes the relevance of findings and benefits, particularly emphasizing the importance of diverse participant inclusion.
- Researchers implemented patient-centered, data-driven strategies, such as using relatable and flexible recruitment methods, to ensure a diverse sample of parents and children in a pediatric genome sequencing study.
- As a result, a high percentage of eligible participants agreed to enroll (93.5% acceptance) and the majority of those who enrolled completed the study, demonstrating the effectiveness of engaging with underrepresented communities.
Despite being outside of the traditionally defined photosynthetically active radiation (PAR) waveband (400-700 nm), far-red (FR; 700-799 nm) light can increase photosynthesis and induce shade-avoidance responses, which increases light interception and thus, whole-plant growth. However, it is unclear how the promotion of growth from FR light depends on PAR wavebands and specifically how the substitution of red light (600-699 nm) with green light (500-599 nm) influences the efficacy of FR light on increasing shoot biomass accumulation. To determine this, we grew red- and green-leaf lettuce (Lactuca sativa) at a fixed total photon flux density (PFD) with 12 different fractions of red, green, and FR light and the same PFD of blue (400-499 nm) light.
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