Publications by authors named "N Maejima"

Article Synopsis
  • - A newborn male developed a mild bite wound on a cephalohematoma from an indoor dog at 10 days old, which led to a severe infection by a well-known bacteria.
  • - After presenting to a hospital with a fever and septic shock, the child's condition worsened, revealing multiple brain lesions and complications including hydrocephalus.
  • - The report highlights that neonates are particularly susceptible to severe infections, often resulting in neurological issues, even without direct trauma, emphasizing the risks associated with animal bites.
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  • High platelet-derived thrombogenicity in STEMI patients correlates with poor outcomes, and this study investigates the impact of acute inflammation on this condition.
  • The research included 150 STEMI patients, measuring platelet-derived thrombogenicity and peak leukocyte counts to assess inflammatory responses.
  • Findings indicate that patients with higher leukocyte counts exhibited significantly increased platelet-derived thrombogenicity and higher creatine kinase levels, highlighting leukocyte count as an independent factor influencing thrombogenicity during primary PCI.
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Neurological complications are frequent non-respiratory complications associated with coronavirus disease 2019 (COVID-19), and acute encephalopathy (AE) has been reported to occur in 2.2% of patients. Among many phenotypes of AEs, acute necrotizing encephalopathy (ANE) is associated with multiple organ failure (MOF), leading to severe neurological morbidity and mortality.

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  • * Involving 410 patients, those with LDL-C levels less than 122 mg/dL faced a 2.3 times higher risk of serious health events (like death, heart attacks, and strokes) over a median follow-up of 6.1 years, compared to higher LDL-C patients.
  • * Key factors linked to poor outcomes in the low LDL-C group were identified as frailty (slow gait speed), chronic inflammation (high C-reactive protein), and endothelial dysfunction.
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  • Endothelial dysfunction increases the risk of major bleeding and adverse cardiovascular events in patients with acute coronary syndrome, as shown in a study of 674 patients over 6.1 years.
  • 39.2% of patients were identified with endothelial dysfunction, which was linked to a greater likelihood of major bleeding (hazard ratio 2.29) and major cardiovascular events (hazard ratio 2.04).
  • The study concluded that assessing endothelial dysfunction using the reactive hyperaemia index can help predict future cardiovascular issues and increased risk of cardiovascular death, while no association with non-cardiovascular death was found.
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