Publications by authors named "N M van Popele"
Objectives: Aortic stiffness is an independent predictor of cardiovascular morbidity and mortality. We investigated whether aortic stiffness, estimated as aortic pulse wave velocity, is associated with decreased perfusion pressure estimated as the cardiac oxygen supply potential.
Methods: Aortic stiffness and aortic pressure waves, reconstructed from finger blood pressure waves, were obtained in 2490 older adults within the framework of the Rotterdam Study, a large population-based study.
Objective: Aortic stiffness can lead to low diastolic blood pressure, thereby possibly limiting coronary perfusion. Therefore, the simultaneous occurrence of both aortic stiffness and coronary atherosclerosis can lead to an increased risk of subendocardial ischaemia. The aim of the present study was to investigate the association between aortic stiffness and coronary atherosclerosis.
View Article and Find Full Text PDFObjectives: To study the association between impaired fasting glucose (IFG) and arterial stiffness in older adults.
Design: Cross-sectional population-based study.
Setting: The Rotterdam Study, a Dutch population-based cohort study.
Background: Arterial stiffness has been associated with the risk of cardiovascular disease in selected groups of patients. We evaluated whether arterial stiffness is a predictor of coronary heart disease and stroke in a population-based study among apparently healthy subjects.
Methods And Results: The present study included 2835 subjects participating in the third examination phase of the Rotterdam Study.
Objectives: To compare the strength of the relative risks of systolic (SBP) diastolic blood pressure (DBP) and pulse pressure (PP) as predictors of myocardial infarction and stroke in older adults.
Design: Prospective cohort study.
Setting: The Rotterdam Study, a Dutch population-based study.