[Streptoverticillium griseoviridum n. sp., a producer of the candidin-amphotericin B group, antifungal heptaene nonaromatic antibiotic 0185].

An actinomyceteous strain LIA-0185 producing a heptaenic non-aromatic antibiotic of the candidin type was isolated from a soil sample taken in the Georgian SSR under the programme of screening antifungal antibiotics. The taxonomic study of the strain showed that it belonged to the series of viridoflavum and had the following main taxonomic features: the sporophores in the whorls, straight, remote: the aerial mycelium from yellow to dark-olive-grey; the substrate mycelium olive; the soluble pigment absent; the melanine pigment was produced on the peptone medium; the culture formed H2S; assimilated glucose, mannose, inozide and to a lesser extent fructose; did not assimilate arabinose, xylose, sucrose, lactose, ramnose and raffinose. The strain inhibited the growth of yeast and fungi, grampositive bacteria and actinomycetes and produced a complex of non-aromatic heptaenic antibiotics.

[Rubrofugal influences on the spike activity of neurons of the medial reticulo-spinal tract].

Synaptic influences from the red nucleus on the activity of the medial reticulo-spinal tract fibres were studied by microelectrode recording in throacic spinal cord of an anesthetized cat. It is found that the red nucleus establishes monosynaptic connections with many pontine and medullary reticulo-spinal neurons with fast (60-105 m/s) and moderate conducting (45-60 m/s) axons. Background activity of these fibres (characterized by grouping of impulses) is accelerated by repetitive stimulation of the red nucleus.