[An exploratory study of test anxiety management workshop based on the Unified Protocol].

Introduction: Test anxiety is a multidimensional construct, defined as a set of phenomenological, physiological and behavioral responses associated with cognitive processes linked to excessive concern about possible negative consequences in an evaluative situation. In university students, it presents occurrence rates between 10 % and 40 %. Therefore, the main objective of the present study is to evaluate the usefulness of a group and online workshop for managing this problem based on the Unified Protocol.

A rapid and simple method for the determination of psychoactive alkaloids by CE-UV: application to Peganum Harmala seed infusions.

The β-carboline alkaloids of the harmala (HAlks) group are compounds widely spread in many natural sources, but found at relatively high levels in some specific plants like Peganum harmala (Syrian rue) or Banisteriopsis caapi. HAlks are a reversible Mono Amino Oxidase type A Inhibitor (MAOI) and, as a consequence, these plants or their extracts can be used to produce psychotropic effects when are combined with psychotropic drugs based on amino groups. Since the occurrence and the levels of the HAlks in natural sources are subject to significant variability, more widespread use is not clinical but recreational or ritual, for example B.

A helix-coil transition induced by the metal ion interaction with a grafted iron-binding site of the CyaY protein family.

Iron-protein interactions are involved in electron transfer reactions. Alterations of these processes are present in a number of human pathologies; among them, in Friedreich's ataxia, in which a deficiency of functional frataxin, an iron-binding protein, leads to progressive neuromuscular degenerative disease. The putative iron-binding motif of acidic residues EExxED was selected from the first α-helical stretch of the frataxin protein family and grafted onto a foreign peptide scaffold corresponding to the C-terminal α-helix from E.

Study of peptide-ligand interactions in open-tubular capillary columns covalently modified with porphyrins.

The inner surface of fused silica capillaries has been covalently modified with different porphyrins (deuteroporphyrin, complexes of deuteroporphyrin with metal ions Fe(III), Cu(II), Zn(II), Ni(II), and Cu(II)-meso-tetra (carboxyphenyl) porphyrin) and it was applied for the separation of biologically active peptides by open-tubular capillary electrochromatography. Separations were performed in a mobile phase composed of 25 mM potassium phosphate, pH 4.0, 5% v/v ACN and 10 mM hydroquinone.

On-line solid phase extraction CZE for the simultaneous determination of lanthanum and gadolinium at picogram per liter levels.

A non-specific on-line method is presented for the extraction and preconcentration of two rare earth elements using a microcartridge containing C(18)-derivatized silica particles prior to their analysis by CZE. The microcartridge, named analyte concentrator, was coupled on-line to the inlet of the separation capillary (fused-silica (FS) capillary, 75 microm id x12 cm from the inlet to the microcartidge and 37 cm from the microcartridge to the detector). The reversed-phase sorbent quantitatively retained gadolinium (Gd) and lanthanum (La) as 2-(5-bromo-2-pyridylazo)-5-diethylaminophenol complexes in the presence of non-ionic micelles of polyethylene glycol tert-octylphenyl ether, enabling sample clean-up and concentration enhancement with minimum sample handling.