Radiomics for prediction of perineural invasion in colorectal cancer: a systematic review and meta-analysis.

Background: Perineural invasion (PNI) in colorectal cancer (CRC) is a significant prognostic factor associated with poor outcomes. Radiomics, which involves extracting quantitative features from medical imaging, has emerged as a potential tool for predicting PNI. This systematic review and meta-analysis aimed to evaluate the diagnostic accuracy of radiomics models in predicting PNI in CRC.

Knowledge, Attitude, and Practice Toward Pelvic Floor Dysfunction Among Postpartum and Postmenopausal Women: A Cross-sectional Study.

Introduction And Hypothesis: This research sought to explore the knowledge, attitude, and practice (KAP) toward pelvic floor dysfunction (PFD) among postpartum and postmenopausal women.

Methods: This cross-sectional study was performed among postpartum and postmenopausal women between May and August 2023. Demographic data, along with KAP scores, were collected using a self-designed questionnaire-based approach.

The molecular mechanism of transforming red light signal to (E)-β-caryophyllene biosynthesis in Arabidopsis.

It is known that red light irradiation enhances the biosynthesis of (E)-β-caryophyllene in plants. However, the underlying mechanism connecting red light to (E)-β-caryophyllene biosynthesis remains elusive. This study reveals a molecular cascade involving the phyB-PIF4-MYC2 module, which regulates (E)-β-caryophyllene biosynthesis in response to the red light signal in Arabidopsis thaliana.

Sex-specific cut-off for dilute Russell's viper venom time lupus anticoagulant test may be of value.

Background: Current guidelines recommend application of the 99th percentile to determine the cut-off value on at least 120 healthy donors regardless of sex for lupus anticoagulant (LA) ratio of each step. However, a statistically significant difference between the sexes has been found for LA ratio recently.

Objectives: To clarify whether this sex difference in dilute Russell's viper venom time (DRVVT) exists in various detection systems and the necessity of setting sex-specific cut-off values.

Irisin-mediated KEAP1 degradation alleviates oxidative stress and ameliorates pancreatitis.

Oxidative stress (OS) injury is pivotal in acute pancreatitis (AP) pathogenesis, contributing to inflammatory cascades. Irisin, a ubiquitous cytokine, exhibits antioxidant properties. However, the role of irisin in AP remains inconclusive.