Antipsoriatic activity of extracts and fractions obtained from Memecylon malabaricum leaves.

Objectives: This study involves the evaluation of Memecylon malabaricum Cogn. (Melastomataceae) leaves for antipsoriatic activity.

Methods: Aqueous extract, hydroalcoholic extract and their fractions of M.

Aβ(42) induced MRI changes in aged rabbit brain resembles AD brain.

Alzheimer's disease is the most common form of dementia and is structurally characterized by brain atrophy and loss of brain volume. Aβ is one of the widely accepted causative factors of AD. Aβ deposition is positively correlated with brain atrophy in AD.

Screening of Caesalpinia bonduc leaves for antipsoriatic activity.

Ethnopharmacological Relevance: Leaves of Caesalpinia bonduc (L.) Roxb. (Caesalpiniaceae) have been used by traditional Siddha healer of Malabar region for psoriasis treatment.

New evidence on iron, copper accumulation and zinc depletion and its correlation with DNA integrity in aging human brain regions.

Deoxyribonucleic acid (DNA) conformation and stability play an important role in brain function. Earlier studies reported alterations in DNA integrity in the brain regions of neurological disorders like Parkinson's and Alzheimer's diseases. However, there are only limited studies on DNA stability in an aging brain and the factors responsible for genomic instability are still not clear.