Genetic characteristics of the Georgian population.

Allele and haplotype frequencies were determined for seven blood group genetic markers on a random sample of 366 individuals from two Georgian villages-Saberio and Alisubani. Genetic distance analysis shows that Georgians can be placed between the populations from the Northern Caucasian (West and Central) areas and the trans-Caucasian ethnic groups. An examination of the genetic relationship of Georgians with European and West Asian populations showed that Georgians are approximately equidistant from the groups compared.

Genetic polymorphisms in a rural Osetian community.

Data are presented on ABO, Rhesus, MNSs, P, Duffy, Kell and Kidd blood group polymorphisms in the Dzhava district, located on the southern slopes of the Main Caucasian Mountain Range. The gene frequencies, compared with those in other Osetian populations and neighbouring ethnic groups of the Caucasus, show general similarity. An exception to the general pattern is presented only by the P blood group system, where the frequencies of the alleles are significantly different form those observed in the neighbouring populations.

[Experimental basis and clinical results of the use of short-term hyperglycemia in combined therapy of malignant tumors].

Proceeding from an analysis of the literature and their own data on radio- and thermodifying properties of hyperglycemia the authors have proposed a scheme of polyfactor therapy of malignant tumors including the following succession of exposures under clinical conditions: irradiation (the 1st fraction)--a chemotherapeutic drug--hyperglycemia--hyperthermia--irradiation (the 2nd fraction). The interval between exposures should be the least, best of all exposures should follow one another in a quick succession. Using the experimental data for determination of methods of therapy of transition and metastatic tumors of the upper respiratory tracts, satisfactory clinical results were obtained with regard to survival and the absence of local radiation reactions.