Knowledge, Attitude, and Practice Towards Antibiotics Use Among Medical Sector Final-Year Students in Egypt.

Introduction: Medical sector students must be well-educated and competent to spread public awareness of antibiotics among the public to combat antibiotic resistance. This study aimed to assess the knowledge, attitude, and practice (KAP) of students regarding antibiotic use and resistance in Egypt.

Methodology: A cross-sectional questionnaire was specially designed and self-administered by final-year students (medicine (MS), pharmacy (PS), dentistry (DS), and nursing (NS)) during the last semester at nine universities.

Enhancing the structural and optoelectronic properties of carboxymethyl cellulose sodium filled with ZnO/GO and CuO/GO nanocomposites for antimicrobial packaging applications.

One of the biggest challenges in food packaging is the creation of sustainable and eco-friendly packaging materials to shield foods from ultraviolet (UV) photochemical damage and to preserve the distinctive physical, chemical, and biological characteristics of foods throughout the supply chain. Accordingly, this study focuses on enhancing the UV shielding properties and biological activity of carboxylmethyl cellulose sodium (CMC) through modifications using zinc oxide (ZnO), copper oxide (CuO), and graphene oxide (GO) using the solution casting technique. The hybrid nanocomposites were characterized by fourier-transform infrared (FTIR) spectrophotometer, ultraviolet-visible (UV-Vis) spectrophotometer, scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), and x-ray diffraction (XRD).

Perindopril Ameliorates Sodium Valproate-Induced Rat Model of Autism: Involvement of Sirtuin-1, JAK2/STAT3 Axis, PI3K/Akt/GSK-3β Pathway, and PPAR-Gamma Signaling.

Autism is a developmental disability characterized by impairment of motor functions and social communication together with the development of repetitive or stereotyped behaviors. Neither the exact etiology or the curative treatment of autism are yet completely explored. The goals of this study were to evaluate the possible effects of perindopril on a rat model of autism and to elucidate the possible molecular mechanisms that may contribute to these effects.

Repurposing of erythropoietin as a neuroprotective agent against methotrexate-induced neurotoxicity in rats.

Background: Methotrexate (MTX) is a cytotoxic drug that can trigger neurotoxicity via enhancing oxidative stress, apoptosis, and inflammation. On the other hand, erythropoietin (EPO) functions as an antioxidant, anti-apoptotic, and anti-inflammatory agent, in addition to its hematopoietic effects.

Aim: The present study was developed to examine the neuroprotective impact of EPO against MTX-provoked neurotoxicity in rats.

Role of SiO, TiO, and FeO adsorbed on glycine for remediation of heavy metals and antibacterial activity in water.

Metals have a tendency to accumulate in the environment and can have carcinogenic effects. Accordingly, this study used density functional theory (DFT) calculations to investigate the adsorption of different metal ions on the glycine surface. Glycine has attracted a lot of research interest because of its remarkable metal-binding properties and cost effectiveness.