Publications by authors named "N M Nenasheva"

Article Synopsis
  • A fungal pathogen affecting low-input apple production has become more widespread in Europe over the past 15 years, yet little is known about its biology and ability to cause disease.
  • This study focused on strain DC1_JKI from Germany, which was sequenced to achieve a comprehensive genome assembly, revealing a mating-type locus identified as MAT1-2.
  • Analysis across European and Asian samples showed that only MAT1-2 was present in European samples, potentially explaining the absence of the sexual reproduction form of the pathogen in European apple orchards.
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Background: Over 40 years of use demonstrates that complement 1 esterase inhibitor (C1-INH) concentrate is effective and well tolerated for acute edema attacks and prophylaxis in patients with hereditary angioedema. OCTA-C1-INH is a new stable, virus-inactivated, nanofiltrated concentrate of C1-INH derived from human plasma.

Objective: We investigated the pharmacokinetics and safety profile of new C1-INH in people with hereditary angioedema during an attack-free period.

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Article Synopsis
  • Vaccination is essential for controlling COVID-19, but hesitancy is a challenge, especially among patients with severe asthma; this study explores their vaccination experiences.
  • A questionnaire was distributed to patients with severe asthma across 12 European countries, revealing that 88% of participants had been or planned to be vaccinated, while 9.5% hesitated and 3% refused; beliefs about vaccines influenced these decisions.
  • Most patients reported mild or no side effects and noted minimal impact on asthma symptoms post-vaccination, with nearly all vaccinated individuals recommending the vaccine to others in their situation.
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Background: The Earth Biogenome Project has rapidly increased the number of available eukaryotic genomes, but most released genomes continue to lack annotation of protein-coding genes. In addition, no transcriptome data is available for some genomes.

Results: Various gene annotation tools have been developed but each has its limitations.

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The Earth Biogenome Project has rapidly increased the number of available eukaryotic genomes, but most released genomes continue to lack annotation of protein-coding genes. In addition, no transcriptome data is available for some genomes. Various gene annotation tools have been developed but each has its limitations.

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