Publications by authors named "N M Naim"
Article Synopsis
- * A systematic search of literature led to the selection of 60 case-control studies, categorized into eight areas including gene expression, SNPs, and miRNA studies, highlighting several key genes commonly associated with APS.
- * The research emphasizes the need for further investigation into these genes and pathways to potentially identify biomarkers for APS, which could assist in the diagnosis and treatment of the condition.
Article Synopsis
- Obesity is a serious global health issue affecting many countries, and traditional medical treatments have often been ineffective, making bariatric surgeries like sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB) the primary options for severe cases.
- A newer alternative, one-anastomosis gastric bypass (OAGB), simplifies procedures compared to RYGB and shows promising initial results, although there are ongoing concerns regarding biliary reflux.
- A systematic review of 12 studies involving 1,057 patients compared RYGB and OAGB, revealing that while OAGB had advantages in BMI reduction, operation time, and complications, RYGB was better for excess weight and BMI loss. *
Neurological symptoms that occur before the diagnosis of primary Sjögren's syndrome (PSS) can vary and affect either the central nervous system (CNS) or the peripheral nervous system (PNS). Aseptic meningitis, although rare, can be an initial central neurological sign of PSS. This case report describes a 54-year-old patient who was initially presented with aseptic meningitis and was subsequently diagnosed with PSS.
View Article and Find Full Text PDFBackground: The widespread evolution of pesticide resistance poses a significant challenge to current agriculture, necessitating the discovery of molecules with new modes of action. Despite extensive efforts, no major molecules with new modes of action have been commercialized for decades. Most pesticides function by binding to specific pockets on target enzymes, enabling a single target site mutation to confer resistance.
View Article and Find Full Text PDFOur goal was to accurately track the cellular distribution of an optogenetic protein and evaluate its functionality within a specific cytoplasmic location. To achieve this, we co-transfected cells with nuclear-targeted cAMP sensors and our laboratory-developed optogenetic protein, bacterial photoactivatable adenylyl cyclase-nanoluciferase (bPAC-nLuc). bPAC-nLuc, when stimulated with 445 nm light or luciferase substrates, generates adenosine 3',5'-cyclic monophosphate (cAMP).
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